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TSPAN33 Protein

TSPAN33 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Produktnummer ABIN7491757
  • Target Alle TSPAN33 Proteine anzeigen
    TSPAN33 (Tetraspanin 33 (TSPAN33))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 1
    • 1
    Human
    Quelle
    • 2
    HEK-293 Cells
    Verwendungszweck
    Human TSPAN33 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    TSPAN33 (Tetraspanin 33 (TSPAN33))
    Andere Bezeichnung
    TSPAN33 (TSPAN33 Produkte)
    Synonyme
    zgc:92266 Protein, PEN Protein, 1300010A20Rik Protein, AI035228 Protein, Pen Protein, RGD1560915 Protein, tetraspanin 33 Protein, tetraspanin 33a Protein, tetraspanin 33 L homeolog Protein, TSPAN33 Protein, tspan33a Protein, tspan33.L Protein, Tspan33 Protein
    Hintergrund
    Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).
    Molekulargewicht
    The human full length TSPAN33 protein has a MW of 31.5 kDa
    UniProt
    Q86UF1
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