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CD37 Protein

TSPAN26 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Produktnummer ABIN7491580
  • Target Alle CD37 (TSPAN26) Proteine anzeigen
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 8
    • 1
    Human
    Quelle
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Verwendungszweck
    Human CD37 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    Andere Bezeichnung
    CD37 (TSPAN26 Produkte)
    Synonyme
    Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
    Hintergrund
    The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
    Molekulargewicht
    The human full length CD37 protein has a MW of 31.7 kDa
    UniProt
    P11049
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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