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FSHR Protein

FSHR Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Produktnummer ABIN7491643
  • Target Alle FSHR Proteine anzeigen
    FSHR (Follicle Stimulating Hormone Receptor (FSHR))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    Human
    Quelle
    • 3
    • 1
    HEK-293 Cells
    Verwendungszweck
    Human FSHR full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    FSHR (Follicle Stimulating Hormone Receptor (FSHR))
    Andere Bezeichnung
    FSHR (FSHR Produkte)
    Synonyme
    FSHRO Protein, LGR1 Protein, ODG1 Protein, FSH-R Protein, eFSHR Protein, FSHRE Protein, fshr Protein, FSHR Protein, fshr-A Protein, GTHR-I Protein, zfGTHR-I Protein, LOC100304505 Protein, follicle stimulating hormone receptor Protein, follicle stimulating hormone receptor L homeolog Protein, follicle-stimulating hormone receptor Protein, FSHR Protein, fshr Protein, Fshr Protein, fshr.L Protein, Bm1_17785 Protein, LOC100304505 Protein
    Hintergrund
    The protein belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    The human full length FSHR protein has a MW of 78.3 kDa
    UniProt
    P23945
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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