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CD81 Protein (CD81)

CD81 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Produktnummer ABIN7491588
  • Target Alle CD81 Proteine anzeigen
    CD81
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 11
    • 2
    • 1
    Human
    Quelle
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Verwendungszweck
    Human CD81 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product CD81 Protein
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    CD81
    Andere Bezeichnung
    CD81 (CD81 Produkte)
    Synonyme
    Tapa-1 Protein, Tapa1 Protein, Tspan28 Protein, CVID6 Protein, S5.7 Protein, TAPA1 Protein, TSPAN28 Protein, CD81 molecule Protein, CD81 molecule b Protein, CD81 antigen Protein, Cd81 molecule Protein, CD81 Protein, cd81b Protein, Cd81 Protein
    Hintergrund
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
    Molekulargewicht
    The human full length CD81 protein has a MW of 25.6 kDa
    UniProt
    P60033
    Pathways
    Inositol Metabolic Process, Hepatitis C
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