CMTM6 Protein

Produktnummer ABIN7491615

Produktdetails

Target: CMTM6 (CKLF-Like MARVEL Transmembrane Domain Containing 6 (CMTM6))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human CMTM6 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CMTM6 (CKLF-Like MARVEL Transmembrane Domain Containing 6 (CMTM6))

Andere Bezeichnung: CMTM6 (CMTM6 Produkte)

Synonyme: sb:cb551 Protein, wu:fc75b06 Protein, si:dkey-11p23.2 Protein, CKLFSF6 Protein, MGC127534 Protein, cklfsf6 Protein, DKFZp469L0821 Protein, 2810051A14Rik Protein, AA536733 Protein, Cklfsf6 Protein, PRO2219 Protein, Da2-17 Protein, LRRGT00102 Protein, CKLF-like MARVEL transmembrane domain containing 6 Protein, CKLF like MARVEL transmembrane domain containing 6 Protein, cmtm6 Protein, CMTM6 Protein, Cmtm6 Protein

Hintergrund: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]

Molekulargewicht: The human full length CMTM6 protein has a MW of 20.4 kDa

UniProt: Q9NX76