PTGER2 Protein

Produktnummer ABIN7491719

Produktdetails

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human PTGER2 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Andere Bezeichnung: PTGER2 (PTGER2 Produkte)

Synonyme: EP2 Protein, Ptgerep2 Protein, ptger2 Protein, ptger2l Protein, zgc:63974 Protein, MGC69060 Protein, PTGER2 Protein, Ptger-ep2 Protein, si:ch211-13n20.1 Protein, si:dkey-29m11.3 Protein, zgc:136608 Protein, prostaglandin E receptor 2 Protein, prostaglandin E receptor 2 (subtype EP2) Protein, prostaglandin E receptor 2a (subtype EP2) Protein, prostaglandin E receptor 2 S homeolog Protein, prostaglandin E receptor 2b (subtype EP2) Protein, PTGER2 Protein, Ptger2 Protein, ptger2a Protein, ptger2.S Protein, ptger2b Protein

Hintergrund: This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]

Molekulargewicht: The human full length PTGER2 protein has a MW of 39.6 kDa

UniProt: P43116