TMCC3 Protein

Produktnummer ABIN7491749

Produktdetails

Target: TMCC3 (Transmembrane and Coiled-Coil Domain Family 3 (TMCC3))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human TMCC3 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: TMCC3 (Transmembrane and Coiled-Coil Domain Family 3 (TMCC3))

Andere Bezeichnung: TMCC3 (TMCC3 Produkte)

Synonyme: wu:fb81d10 Protein, wu:fb83h01 Protein, wu:fk68a09 Protein, wu:fl22e07 Protein, si:dkey-183c16.4 Protein, DKFZp469H0211 Protein, AW488095 Protein, C630016B22Rik Protein, C88213 Protein, Tmcc1 Protein, RGD1307241 Protein, transmembrane and coiled-coil domain family 3 Protein, transmembrane and coiled coil domains 3 Protein, tmcc3 Protein, TMCC3 Protein, Tmcc3 Protein

Hintergrund: This protein belongs to the the transmembrane and coiled-coil domain (TMCC) family, which shares common structural motifs (two transmembrane domains and two coiled-coil domains). TMCC3 was isolated as a novel gene isolated from human brain, and later became known as a novel gene up-regulated in the developing brain, especially in the ventral tegmentum. There is no resolved structure or defined function.

Molekulargewicht: The human full length TMCC3 protein has a MW of 53.8 kDa

UniProt: Q9ULS5