TMEM180 Protein

Produktnummer ABIN7491697

Produktdetails

Target: TMEM180 (Transmembrane Protein 180 (TMEM180))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human MFSD13A full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: TMEM180 (Transmembrane Protein 180 (TMEM180))

Andere Bezeichnung: MFSD13A (TMEM180 Produkte)

Synonyme: C10orf77 Protein, bA18I14.8 Protein, 4930449A08Rik Protein, 4930538D17Rik Protein, major facilitator superfamily domain containing 13A Protein, major facilitator superfamily domain containing 13a Protein, MFSD13A Protein, Mfsd13a Protein

Hintergrund: MFSD13A, also called Transmembrane protein 180 (TMEM180), is a transmembrane protein that belongs to the glycoside-pentoside-hexuronide (GPH):cation symporter family. Members of this family catalyze symport of a sugar molecule with a monovalent cation (H or Na ). MFSD13A is classified as a member of the cation symporter family and a multi-pass membrane protein, but little information is available regarding its substrate and topology.

Molekulargewicht: The human full length MFSD13A protein has a MW of 57.4 kDa

UniProt: Q14CX5