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F2RL3 Protein

F2RL3 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Produktnummer ABIN7491639
  • Target Alle F2RL3 Proteine anzeigen
    F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
    Protein-Typ
    Synthetic Nanodisc
    Spezies
    • 5
    • 2
    Human
    Quelle
    • 3
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Verwendungszweck
    Human F2RL3 full length protein-synthetic nanodisc
    Produktmerkmale
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
    Andere Bezeichnung
    F2RL3 (F2RL3 Produkte)
    Synonyme
    F2RL3 Protein, PAR4 Protein, F2R like thrombin or trypsin receptor 3 Protein, F2R like thrombin/trypsin receptor 3 Protein, coagulation factor II (thrombin) receptor-like 3 Protein, F2RL3 Protein, F2rl3 Protein
    Hintergrund
    A member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.
    Molekulargewicht
    The human full length F2RL3 protein has a MW of 41.1 kDa
    UniProt
    Q96RI0
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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