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CXCR6 Protein-VLP

CXCR6 Spezies: Human Wirt: HEK-293 Cells VLP
Produktnummer ABIN7489101
  • Target Alle CXCR6 Proteine anzeigen
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    Protein-Typ
    VLP
    Spezies
    • 6
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Verwendungszweck
    Human CXCR6 / CD186 Full Length Protein (VLP)
    Sequenz
    Ala 2 - Leu 342
    Produktmerkmale
    Human CXCR6 Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Leu 342 (Accession # O00574-1).
    Endotoxin-Niveau
    1.0 EU per μg
    Top Product
    Discover our top product CXCR6 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, Arginine, pH 7.4
    Lagerung
    -80 °C
    Informationen zur Lagerung
    -70°C
  • Target
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    Andere Bezeichnung
    CXCR6 (CXCR6 Produkte)
    Synonyme
    BONZO Protein, CD186 Protein, STRL33 Protein, TYMSTR Protein, BB217514 Protein, C-X-C motif chemokine receptor 6 Protein, chemokine (C-X-C motif) receptor 6 L homeolog Protein, chemokine (C-X-C motif) receptor 6 Protein, CXCR6 Protein, cxcr6.L Protein, Cxcr6 Protein
    Hintergrund
    The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
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