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NKG2A & CD94 protein (His tag)

Spezies: Human Wirt: HEK-293 Cells Recombinant 95 %
Produktnummer ABIN7482528
  • Target
    NKG2A & CD94
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 3
    • 1
    Human
    Quelle
    • 14
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    His tag
    Verwendungszweck
    Human NKG2A&CD94 Protein, His Tag
    Sequenz
    Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
    Produktmerkmale
    Human NKG2A&CD94 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # P26715-1 (NKG2A) & Q13241-1 (CD94).
    Reinheit
    95 %
    Endotoxin-Niveau
    1.0 EU per μg
  • Kommentare

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 30.7 kDa. The protein migrates as 37-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    NKG2A & CD94
    Andere Bezeichnung
    NKG2A&CD94
    Hintergrund
    CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
    Molekulargewicht
    30.7 kDa
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