CEACAM5 Protein (AA 35-685) (Biotin)

Produktnummer ABIN7504291

Produktdetails

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 35-685

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CEACAM5 Protein ist gelabelt mit Biotin.

Verwendungszweck: Biotinylated Human CEACAM-5/CD66e Protein

Sequenz: Lys35-Ala685

Produktmerkmale: Recombinant Biotinylated Human CEACAM-5/CD66e Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Lys35-Ala685.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Andere Bezeichnung: CEACAM-5 (CEACAM5 Produkte)

Synonyme: CD66e Protein, CEA Protein, CEACAM5 Protein, CEACAM Protein, 1600029H12Rik Protein, Psg30 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen Protein, carcinoembryonic antigen-related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 8 Protein, carcinoembryonic antigen gene family Protein, CEACAM5 Protein, Ceacam5 Protein, LOC100409241 Protein, Cea Protein

Hintergrund: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Molekulargewicht: 74.23 kDa. Due to glycosylation, the protein migrates to 110-150 kDa based on Tris-Bis PAGE result.