CEACAM5 Protein (AA 145-322) (His tag)

Produktnummer ABIN7504293

Produktdetails

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 145-322

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CEACAM5 Protein ist gelabelt mit His tag.

Verwendungszweck: Human CEACAM-5/CD66e Protein

Sequenz: Pro145-Pro322

Produktmerkmale: Recombinant Human CEACAM-5/CD66e (145-322) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro145-Pro322.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Andere Bezeichnung: CEACAM-5 (CEACAM5 Produkte)

Synonyme: CD66e Protein, CEA Protein, CEACAM5 Protein, CEACAM Protein, 1600029H12Rik Protein, Psg30 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen Protein, carcinoembryonic antigen-related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 8 Protein, carcinoembryonic antigen gene family Protein, CEACAM5 Protein, Ceacam5 Protein, LOC100409241 Protein, Cea Protein

Hintergrund: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Molekulargewicht: 20.66 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.