C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) Protein
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- Target Alle C-Type Lectin Domain Family 4, Member M (CLEC4M) Proteine anzeigen
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 71-399
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human CLEC4M/CD299 Protein
- Sequenz
- Gln71-Glu399
- Produktmerkmale
- Recombinant Human CLEC4M/CD299 Protein is expressed from HEK293 without tag.It contains Gln71-Glu399.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC4M Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Andere Bezeichnung
- CLEC4M (CLEC4M Produkte)
- Synonyme
- CD209L Protein, CD299 Protein, DC-SIGN2 Protein, DC-SIGNR Protein, DCSIGNR Protein, HP10347 Protein, L-SIGN Protein, LSIGN Protein, CD209B Protein, C-type lectin domain family 4 member M Protein, CLEC4M Protein
- Hintergrund
- CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance.
- Molekulargewicht
- 37.72 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Tris-Bis PAGE result.
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