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FLT3 Protein (AA 27-541) (Biotin)

FLT3 Spezies: Human Wirt: CHO Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7504335
  • Target Alle FLT3 Proteine anzeigen
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 27-541
    Spezies
    • 19
    • 7
    • 1
    Human
    Quelle
    • 14
    • 7
    • 3
    • 1
    • 1
    • 1
    CHO Cells
    Aufreinigungstag / Konjugat
    Dieses FLT3 Protein ist gelabelt mit Biotin.
    Verwendungszweck
    Biotinylated Human FLT3/Flk-2 Protein
    Sequenz
    Asn27-Asn541
    Produktmerkmale
    Recombinant Biotinylated Human FLT3/Flk-2 Protein is expressed from CHO with His tag and Avi tag at the C-Terminus.It contains Asn27-Asn541.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product FLT3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Andere Bezeichnung
    FLT3 (FLT3 Produkte)
    Synonyme
    FLT3 Protein, B230315G04 Protein, CD135 Protein, Flk-2 Protein, Flk2 Protein, Flt-3 Protein, Ly72 Protein, wmfl Protein, FLK-2 Protein, FLK2 Protein, STK1 Protein, fms related tyrosine kinase 3 Protein, FMS-like tyrosine kinase 3 Protein, fms-related tyrosine kinase 3 Protein, FLT3 Protein, Flt3 Protein
    Hintergrund
    The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.
    Molekulargewicht
    61.20 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
    Pathways
    RTK Signalweg
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