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HLA-A*02:01 (Monomer) protein (MAGE-A10)

Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7504370
  • Target
    HLA-A*02:01
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Monomer
    Spezies
    • 70
    • 4
    Human
    Quelle
    • 65
    • 4
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    MAGE-A10
    Verwendungszweck
    Human HLA-A*02:01 & B2M & MAGE-A10 (GLYDGMEHL) Monomer Protein
    Sequenz
    Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and GLYDGMEHL peptide
    Spezifität
    Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), GLYDGMEHL
    Produktmerkmale
    Recombinant Human HLA-A*02:01 & B2M & MAGE-A10 (GLYDGMEHL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HLA-A*02:01
    Hintergrund
    MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.
    Molekulargewicht
    50.44 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A140T913
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