HLA-A*02:01 (Monomer) protein (MAGE-A10)

Produktnummer ABIN7504370

Produktdetails

Target: HLA-A*02:01

Protein-Typ: Recombinant

Proteineigenschaft: Monomer

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: MAGE-A10

Verwendungszweck: Human HLA-A*02:01 & B2M & MAGE-A10 (GLYDGMEHL) Monomer Protein

Sequenz: Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and GLYDGMEHL peptide

Spezifität: Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), GLYDGMEHL

Produktmerkmale: Recombinant Human HLA-A*02:01 & B2M & MAGE-A10 (GLYDGMEHL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: HLA-A*02:01

Hintergrund: MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.

Molekulargewicht: 50.44 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

UniProt: A0A140T913