IL23A Protein (AA 20-189) (His tag)
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- Target Alle IL23A Proteine anzeigen
- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 20-189
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL23A Protein ist gelabelt mit His tag.
- Verwendungszweck
- Human IL-23 alpha & IL-12 beta Protein
- Sequenz
- Arg20-Pro189 (IL-23 alpha) & Ile23-Ser328 (IL-12 beta)
- Spezifität
- Uni-Prot: Q9NPF7 (IL-23 alpha), P29460 (IL-12 beta)
- Produktmerkmale
- Recombinant Human IL-23 alpha & IL-12 beta Protein is expressed from HEK293 with His tag at the C-terminus.It contains Arg20-Pro189(IL-23 alpha) & Ile23-Ser328(IL-12 beta).
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product IL23A Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
- Andere Bezeichnung
- IL-23 alpha (IL23A Produkte)
- Synonyme
- IL-23 Protein, IL-23A Protein, IL23P19 Protein, P19 Protein, SGRF Protein, FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, p19 Protein, il23p19 Protein, IL23 Protein, interleukin 23 subunit alpha Protein, interleukin 37 Protein, interleukin 23, alpha subunit p19 Protein, IL23A Protein, IL37 Protein, Il23a Protein
- Hintergrund
- The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD). Targeting this pathway has opened new avenues for therapeutic intervention. The balance of proinflammatory cytokines interleukin (IL)-12 and IL-23 plays a key role in shaping the development of antitumor or protumor immunity.
- Molekulargewicht
- 19.77 kDa (IL-23 alpha) and 34.7 kDa (IL-12 beta). Due to glycosylation, the protein migrates to 23 kDa (IL-23 alpha) and 40-50 kDa (IL-12 beta) based on Tris-Bis PAGE result.
- UniProt
- Q9NPF7
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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