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ITCH Protein (AA 485-862)

ITCH Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Produktnummer ABIN7504453
  • Target Alle ITCH Proteine anzeigen
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 485-862
    Spezies
    • 3
    • 1
    • 1
    Human
    Quelle
    • 2
    • 1
    Escherichia coli (E. coli)
    Verwendungszweck
    Human ITCH Protein
    Sequenz
    Arg485-Glu862
    Produktmerkmale
    Recombinant Human ITCH Protein is expressed from E.coli without tag.It contains Arg485-Glu862.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product ITCH Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS, 200 mM L-Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    Andere Bezeichnung
    ITCH (ITCH Produkte)
    Synonyme
    AIF4 Protein, AIP4 Protein, NAPP1 Protein, dJ468O1.1 Protein, 6720481N21Rik Protein, 8030492O04Rik Protein, A130065M08 Protein, C230047C07Rik Protein, itchy E3 ubiquitin protein ligase Protein, itchy, E3 ubiquitin protein ligase Protein, ITCH Protein, Itch Protein
    Hintergrund
    Itch or itchy E3 is a member of the homologous to E6-associated protein C-terminus (HECT)-type family of E3 ligases, with the protein-interacting WW-domains for the recruitment of substrate and the HECT domain for the transfer of ubiquitin to the substrate, and its deletion results in an itchy phenotype with constant skin scratching and multi-organ inflammation.
    Molekulargewicht
    44.98 kDa same as Tris-Bis PAGE result.
    NCBI Accession
    NP_113671
    Pathways
    Activation of Innate immune Response, CXCR4-mediated Signaling Events
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