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NOG Protein (AA 28-232)

NOG Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7504481
  • Target Alle NOG Proteine anzeigen
    NOG (Noggin (NOG))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 28-232
    Spezies
    • 11
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Maus
    Quelle
    • 19
    • 7
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    Verwendungszweck
    Mouse Noggin Protein
    Sequenz
    Gln28-Cys232
    Produktmerkmale
    Recombinant Mouse Noggin Protein is expressed from HEK293 without tag.It contains Gln28-Cys232.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product NOG Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS, 100 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NOG (Noggin (NOG))
    Andere Bezeichnung
    Noggin (NOG Produkte)
    Synonyme
    SYM1 Protein, SYNS1 Protein, nog-A Protein, nog1 Protein, noggin-1 Protein, noggin Protein, noggin Protein, noggin L homeolog Protein, noggin protein Protein, NOG Protein, Nog Protein, nog.L Protein, noggin Protein
    Hintergrund
    Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β-catenin, EGFR, ERK and Akt.
    Molekulargewicht
    23.07 kDa. Due to glycosylation, the protein migrates to 28-33 kDa based on Tris-Bis PAGE result.
    UniProt
    P97466
    Pathways
    Stem Cell Maintenance, Tube Formation
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