GTPase NRas Protein (NRAS) (AA 1-186) (His tag)
-
- Target Alle GTPase NRas (NRAS) Proteine anzeigen
- GTPase NRas (NRAS)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-186
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses GTPase NRas Protein ist gelabelt mit His tag.
- Verwendungszweck
- Human NRAS Protein
- Sequenz
- Met1-Cys186
- Produktmerkmale
- Recombinant Human NRAS Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Cys186.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product NRAS Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- GTPase NRas (NRAS)
- Andere Bezeichnung
- NRAS (NRAS Produkte)
- Synonyme
- NRAS Protein, AV095280 Protein, N-ras Protein, ALPS4 Protein, NRAS1 Protein, NS6 Protein, N-RAS Protein, fj99a10 Protein, wu:fj99a10 Protein, zgc:100761 Protein, zras-b1 Protein, H-RAS Protein, HRAS Protein, GTPase NRas Protein, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog Protein, NRAS proto-oncogene, GTPase Protein, neuroblastoma ras oncogene Protein, neuroblastoma RAS viral oncogene homolog Protein, Tsp_01117 Protein, nras.L Protein, Nras Protein, NRAS Protein, nras Protein
- Hintergrund
- NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM.
- Molekulargewicht
- 22.29 kDa same as Tris-Bis PAGE result.
- UniProt
- P01111
- Pathways
- p53 Signalweg, MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
-