SKP1 Protein (AA 2-163) (Biotin)

Produktnummer ABIN7504529

Produktdetails

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-163

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SKP1 Protein ist gelabelt mit Biotin.

Verwendungszweck: Biotinylated Human SKP1 Protein

Sequenz: Pro2-Lys163

Produktmerkmale: Recombinant Biotinylated Human SKP1 Protein is expressed from HEK293 His tag at the N-terminus and Avi tag at the C-terminusIt contains Pro2-Lys163.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Andere Bezeichnung: SKP1 (SKP1 Produkte)

Synonyme: EMC19 Protein, OCP-II Protein, OCP2 Protein, SKP1A Protein, TCEB1L Protein, p19A Protein, 15kDa Protein, 2610043E24Rik Protein, 2610206H23Rik Protein, SKP1 Protein, Tceb1l Protein, p19Skp1 Protein, Skp1a Protein, skp1a Protein, zgc:73186 Protein, ocp2 Protein, emc19 Protein, ocp-ii Protein, tceb1l Protein, ARABIDOPSIS SKP1 HOMOLOGUE 1 Protein, ASK1 Protein, ATSKP1 Protein, S phase kinase-associated protein 1 Protein, T4O12.17 Protein, T4O12_17 Protein, UFO INTERACTING PROTEIN 1 Protein, UIP1 Protein, ocp-2 Protein, S-phase kinase associated protein 1 Protein, S-phase kinase-associated protein 1 Protein, S-phase kinase-associated protein 1 pseudogene Protein, S-phase kinase-associated protein 1A Protein, S-phase kinase-associated protein 1 S homeolog Protein, S phase kinase-associated protein 1 Protein, SKP1 Protein, skp1 Protein, LOC100340043 Protein, Skp1a Protein, Skp1 Protein, skp1.S Protein

Hintergrund: The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulation of downstream biological processes.

Molekulargewicht: 21.43 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.

Pathways: Zellzyklus, Hedgehog Signalweg, Mitotic G1-G1/S Phases