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IL-4 Protein (AA 25-153)

IL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7504977
  • Target Alle IL-4 (IL4) Proteine anzeigen
    IL-4 (IL4) (Interleukin 4 (IL4))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 25-153
    Spezies
    • 29
    • 13
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 38
    • 20
    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    His25-Ser153
    Produktmerkmale
    A DNA sequence encoding the Human IL4 protein (P05112) (His25-Ser153) was expressed with a polyhistidine tag at the N-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    IL-4 (IL4) (Interleukin 4 (IL4))
    Andere Bezeichnung
    IL-4 (IL4 Produkte)
    Synonyme
    IL4 Protein, IL-4 Protein, BCGF-1 Protein, BCGF1 Protein, BSF-1 Protein, BSF1 Protein, Il-4 Protein, Il4e12 Protein, IL2 Protein, interleukin 4 Protein, IL4 Protein, Il4 Protein
    Hintergrund

    Abbreviation: IL-4

    Target Synonym: Interleukin-4,IL4,B-cell stimulatory factor 1,BSF-1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra

    Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

    Molekulargewicht

    Calculated MW: 15 kDa

    Observed MW: 16 kDa

    UniProt
    P05112
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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