THAP1 Protein (AA 1-81) (His tag)
-
- Target Alle THAP1 Proteine anzeigen
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-81
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses THAP1 Protein ist gelabelt mit His tag.
- Sequenz
- Met1-Phe81
- Produktmerkmale
- A DNA sequence encoding theHuman THAP1 protein (Q9NVV9) (Met1-Phe81) was expressed with a N-His.
- Reinheit
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product THAP1 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
-
- Target
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- Andere Bezeichnung
- THAP1 (THAP1 Produkte)
- Synonyme
- THAP1 Protein, thap1-a Protein, DYT6 Protein, 4833431A01Rik Protein, AW490810 Protein, zgc:136597 Protein, THAP domain containing, apoptosis associated protein 1 Protein, THAP domain containing 1 Protein, THAP domain containing, apoptosis associated protein 1 L homeolog Protein, thap1 Protein, THAP1 Protein, thap1.L Protein, Thap1 Protein
- Hintergrund
-
Abbreviation: THAP1
Target Synonym: THAP domain-containing protein 1
Background: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
- Molekulargewicht
-
Calculated MW: 9.5 kDa
Observed MW: 11 kDa
- UniProt
- Q9NVV9
-