UCP1 Protein (AA 1-307) (His tag)

Produktnummer ABIN7505050

Produktdetails

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-307

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UCP1 Protein ist gelabelt mit His tag.

Sequenz: Met 1-Thr 307

Produktmerkmale: A DNA sequence encoding the Human UCP1 protein (P25874) (Met 1-Thr 307) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Andere Bezeichnung: UCP1 (UCP1 Produkte)

Synonyme: ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 Protein, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 Protein, ATPUMP1 Protein, ATUCP1 Protein, UCP Protein, UCP1 Protein, UNCOUPLING PROTEIN 1 Protein, plant uncoupling mitochondrial protein 1 Protein, ucp Protein, slc25a7 Protein, SLC25A7 Protein, AI385626 Protein, Slc25a7 Protein, Ucp Protein, Ucpa Protein, Uncp Protein, plant uncoupling mitochondrial protein 1 Protein, uncoupling protein 1 Protein, uncoupling protein 1 L homeolog Protein, uncoupling protein 1 (mitochondrial, proton carrier) Protein, PUMP1 Protein, UCP1 Protein, ucp1.L Protein, ucp1 Protein, Ucp1 Protein

Hintergrund:

Abbreviation: UCP1

Target Synonym: UCP1,SLC25A7,UCP

Background: Mitochondrial brown fat uncoupling protein 1 (UCP1, also Thermogenin and UCP) is a 33 kDa member of the mitochondrial carrier family of proteins. Human UCP1 are both 307 amino acids (aa) in length and contain three solcar repetitive regions and six transmembrane segments. UCP1 is found in brown adipose tissue, where it becomes activated by fatty acids and inhibited by nucleotides. It functions as a mitochondrial transporter that creates a proton leak across the inner mitochondrial membrane, uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Molekulargewicht:

Calculated MW: 33.66 kDa

Observed MW: 31 kDa

UniProt: P25874

Pathways: Proton Transport, Brown Fat Cell Differentiation