Lactate Dehydrogenase A Protein (LDHA) (AA 2-332) (His tag)

Produktnummer ABIN7505053

Produktdetails

Target: Lactate Dehydrogenase A (LDHA)

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-332

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Lactate Dehydrogenase A Protein ist gelabelt mit His tag.

Sequenz: Ala 2-Phe 332

Produktmerkmale: A DNA sequence encoding the Human LDHA protein (P00338) (Ala 2-Phe 332) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Lactate Dehydrogenase A (LDHA)

Andere Bezeichnung: LDHA (LDHA Produkte)

Synonyme: GSD11 Protein, LDH1 Protein, LDHM Protein, LDH-M Protein, ldh-h Protein, ldha Protein, ldha-B Protein, ldhbb Protein, trg-5 Protein, Ldh1 Protein, Ldhm Protein, l7R2 Protein, gsd11 Protein, ldh-m Protein, ldh1 Protein, ldhm Protein, pig19 Protein, ldha1 Protein, ldhab Protein, LDH-A Protein, LDHC Protein, lactate dehydrogenase A Protein, lactate dehydrogenase B L homeolog Protein, lactate dehydrogenase A4 Protein, lactate dehydrogenase A L homeolog Protein, L-lactate dehydrogenase A chain Protein, LDHA Protein, ldhb.L Protein, Ldha Protein, ldha Protein, ldha.L Protein, LOC100713875 Protein

Hintergrund:

Abbreviation: LDHA

Target Synonym: L-Lactate Dehydrogenase A Chain,LDH-A,Cell Proliferation-Inducing Gene 19 Protein,LDH Muscle Subunit,LDH-M,Renal Carcinoma Antigen NY-REN-59,LDHA

Background: L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.

Molekulargewicht:

Calculated MW: 36.3 kDa

Observed MW: 39 kDa

UniProt: P00338

Pathways: Warburg Effekt