FTH1 Protein (AA 1-183) (His tag)

Produktnummer ABIN7505081

Produktdetails

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-183

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FTH1 Protein ist gelabelt mit His tag.

Sequenz: Met 1-Ser 183

Produktmerkmale: A DNA sequence encoding the Human FTH protein (P02794) (Met 1-Ser 183) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Andere Bezeichnung: FTH (FTH1 Produkte)

Synonyme: FHC Protein, FTH Protein, FTHL6 Protein, PIG15 Protein, PLIF Protein, apoferritin Protein, ferritin Protein, fhc Protein, fth Protein, fth1 Protein, fthl6 Protein, ftn-2 Protein, pig15 Protein, plif Protein, fth1b Protein, Fth Protein, HFt Protein, MFH Protein, fb06g09 Protein, hm:zeh1145 Protein, wu:fb06g09 Protein, wu:fq18c10 Protein, zeh1145 Protein, ferritin heavy chain 1 Protein, ferritin, heavy polypeptide 1 L homeolog Protein, ferritin, heavy polypeptide 1 S homeolog Protein, ferritin heavy polypeptide 1 Protein, ferritin, heavy polypeptide 1a Protein, ferritin Protein, ferritin, heavy polypeptide 1 Protein, tudor domain containing 9 Protein, ferritin, heavy polypeptide 1 a Protein, FTH1 Protein, fth1.L Protein, fth1.S Protein, Fth1 Protein, fth1a Protein, EAMY_RS19690 Protein, fth1 Protein, TDRD9 Protein

Hintergrund:

Abbreviation: FTH

Target Synonym: Ferritin heavy chain,FTH1,FTH,FTHL6,Ferritin H subunit,Cell proliferation-inducing gene 15 protein,FHC,HFE5,PIG15

Background: Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals.

Molekulargewicht:

Calculated MW: 20.02 kDa

Observed MW: 28 kDa

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis