GIP Protein (AA 22-153) (His tag)

Produktnummer ABIN7505083

Produktdetails

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-153

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GIP Protein ist gelabelt mit His tag.

Sequenz: Glu 22-Arg 153

Produktmerkmale: A DNA sequence encoding the Human GIP protein (P09681) (Glu 22-Arg 153) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Andere Bezeichnung: GIP (GIP Produkte)

Synonyme: GIP Protein, xgip Protein, Gludins Protein, RATGLUDINS Protein, gastric inhibitory polypeptide Protein, gastric inhibitory polypeptide L homeolog Protein, GIP Protein, gip Protein, Gip Protein, gip.L Protein

Hintergrund:

Abbreviation: GIP

Target Synonym: gastric inhibitory polypeptide,GIP,Glucose-dependent Insulinotropic Polypeptide,Incretin

Background: Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of hormones. GIP, together with glucagon-like peptide-1 (GLP-1), belongs to the group of metabolic hormones called incretins that stimulate a decrease in blood glucose levels. GIP is derived from a 153-amino acid pro-protein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide. Engagement of Gastric inhibitory polypeptide receptors (GIPR) by GIP on pancreatic beta cells activates adenylate cyclase to regulate insulin compensation in the presence of high circulating glucose.

Molekulargewicht:

Calculated MW: 14.41 kDa

Observed MW: 18 kDa

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism