FLNC Protein (AA 2519-2725) (His tag)
-
- Target Alle FLNC Proteine anzeigen
- FLNC (Filamin C, gamma (FLNC))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 2519-2725
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses FLNC Protein ist gelabelt mit His tag.
- Sequenz
- Thr 2519-Pro 2725
- Produktmerkmale
- A DNA sequence encoding the Human FLNC protein (Q14315) (Thr 2519-Pro 2725) was expressed with a N-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FLNC Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
-
- Target
- FLNC (Filamin C, gamma (FLNC))
- Andere Bezeichnung
- FLNC (FLNC Produkte)
- Synonyme
- 1110055E19Rik Protein, ABP-280 Protein, ABPL Protein, Fln2 Protein, ABP280A Protein, ABPA Protein, FLN2 Protein, MFM5 Protein, MPD4 Protein, filamin C Protein, filamin C L homeolog Protein, filamin C, gamma Protein, FLNC Protein, flnc.L Protein, flnc Protein, Flnc Protein
- Hintergrund
-
Abbreviation: FLNC
Target Synonym: Filamin C ,FIlamin 2,Filamin C,FLN2,FLNC,ABPL,FLN2
Background: FLNC is a muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z-disks in muscle cells. Defects in FLNC are the cause of autosomal dominant filaminopathy. Myofibrillar myopathy (MFM) is a neuromuscular disorder, usually with an adult onset, characterized by focal myofibrillar destruction and pathological cytoplasmic protein aggregations. Autosomal dominant filaminopathy is a form of MFM characterized by morphological features of MFM and clinical features of a limb-girdle myopathy. A heterozygous nonsense mutation which segregates with the disease, has been identified in the FLNC gene.
- Molekulargewicht
-
Calculated MW: 22.66 kDa
Observed MW: 28 kDa
- UniProt
- Q14315
-