Sclerostin Protein (SOST) (AA 24-213) (His tag)
-
- Target Alle Sclerostin (SOST) Proteine anzeigen
- Sclerostin (SOST)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 24-213
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Sclerostin Protein ist gelabelt mit His tag.
- Sequenz
- Gln 24-Tyr 213
- Produktmerkmale
- A DNA sequence encoding the Human SOST protein (Q9BQB4) (Gln24-Tyr213) was expressed with a N-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SOST Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
-
- Target
- Sclerostin (SOST)
- Andere Bezeichnung
- SOST (SOST Produkte)
- Synonyme
- LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein
- Hintergrund
-
Abbreviation: SOST
Target Synonym: CDD,DAND6,SOST1,VBCH
Background: Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
- Molekulargewicht
-
Calculated MW: 20.79 kDa
Observed MW: 28 kDa
- UniProt
- Q9BQB4
-