PODXL Protein (AA 220-431) (SUMO Tag,His tag)

Produktnummer ABIN7505116

Produktdetails

Target: PODXL (Podocalyxin-Like (PODXL))

Protein-Typ: Recombinant

Proteineigenschaft: AA 220-431

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PODXL Protein ist gelabelt mit SUMO Tag,His tag.

Sequenz: Ala 220-Ile 431

Produktmerkmale: A DNA sequence encoding the Human PODXL protein (O00592) (Ala 220-Ile 431) was expressed with a N-SUMO-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: PODXL (PODXL Produkte)

Synonyme: Gp200 Protein, PC Protein, PCLP Protein, PCLP-1 Protein, PCB Protein, AW121214 Protein, Ly102 Protein, Pclp1 Protein, podocalyxin Protein, MEP21 Protein, PODXL Protein, Gp135 Protein, PCLP1 Protein, cPCLP1 Protein, podxl Protein, fc18d02 Protein, wu:fc18d02 Protein, Pc Protein, Pcb Protein, Podxl Protein, podocalyxin like Protein, pyruvate carboxylase Protein, podocalyxin-like Protein, PODXL Protein, PC Protein, Podxl Protein, podxl Protein, Pcx Protein

Hintergrund:

Abbreviation: PODXL

Target Synonym: PCLP,PCLP1,PCLP-1,PCLPGCTM-2 antigen,PCpodocalyxin,POD XL,Podocalyxin,Podocalyxin-like protein 1,podocalyxin-like,PODXL

Background: Podocalyxin (PODXL), also known as Podocalyxin-like protein 1 (PCLP-1), is a heavily glycosylated transmembrane sialoprotein in the CD34 and Endoglycan family.Podocalyxin is expressed on glomerular and vascular endothelial cells, neurons, hematopoietic, mesenchymal, and cardiac stem cells, and metastatic carcinoma and glioblastoma tumor cells. A soluble form of Podocalyxin can be released into the urine of women with pre-eclampsia. Podocalyxin promotes platelet activation, neurite outgrowth, branching, and synaptogenesis, homing of hematopoietic progenitor cells to the bone marrow and spleen, and engraftment of mesenchymal and cardiac stem cells into ischemic heart and kidney. Its interactions with L-Selectin and E-Selectin mediate the tethering of lymphocytes and metastatic tumor cells to the vascular endothelium.

Molekulargewicht:

Calculated MW: 34.21 kDa

Observed MW: 32 kDa

UniProt: O00592

Pathways: Tube Formation