CXCL11 Protein (AA 22-94) (His tag)

Produktnummer ABIN7505135

Produktdetails

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-94

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CXCL11 Protein ist gelabelt mit His tag.

Sequenz: Phe 22-Phe 94

Produktmerkmale: A DNA sequence encoding the Human CXCL11 protein (O14625) (Phe 22-Phe 94) was expressed with a C-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Andere Bezeichnung: CXCL11 (CXCL11 Produkte)

Synonyme: H174 Protein, I-TAC Protein, IP-9 Protein, IP9 Protein, SCYB11 Protein, SCYB9B Protein, b-R1 Protein, Cxc11 Protein, I-tac Protein, Ip9 Protein, Itac Protein, Scyb11 Protein, Scyb9b Protein, betaR1 Protein, C-X-C motif chemokine ligand 11 Protein, chemokine (C-X-C motif) ligand 11 Protein, CXCL11 Protein, Cxcl11 Protein

Hintergrund:

Abbreviation: CXCL11

Target Synonym: Interferon Inducible T-Cell α Chemokine,I-TAC,B-R1,CXCL11,ITAC,SCYB11,SCYB9B

Background: CXCL11, also known as I-TAC, SCYB9B, H174 and beta -R1, is a non-ELR CXC chemokine. CXCL11 cDNA encodes a 94 amino acid (aa) residue precursor protein with a 21 aa residue putative signal sequence, which is cleaved to form the mature 73 aa residue protein. CXCL11 shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG (two other known human non-ELR CXC chemokines), respectively. CXCL11 is expressed at low levels in normal tissues including thymus, spleen and pancreas. The expression of CXCL11 mRNA is radically up regulated in IFN-gamma and IL-1 stimulated astrocytes. Moderate increase in expression is also observed in stimulated monocytes. CXCL11 has potent chemoattractant activity for IL-2 activated T cells and transfected cell lines expressing CXCR3, but not freshly isolated T cells, neutrophils or monocytes. The gene encoding CXCL11 has been mapped to chromosome 4.

Molekulargewicht:

Calculated MW: 7.92 kDa

Observed MW: 12 kDa

UniProt: O14625