Calnexin Protein (CANX) (AA 21-300) (His tag)
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- Target Alle Calnexin (CANX) Proteine anzeigen
- Calnexin (CANX)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 21-300
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Calnexin Protein ist gelabelt mit His tag.
- Sequenz
- His 21-Lys 300
- Produktmerkmale
- A DNA sequence encoding the CANX/Calnexin protein (P27824) (His 21-Lys 300) was expressed with a N-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CANX Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
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- Target
- Calnexin (CANX)
- Andere Bezeichnung
- CANX (CANX Produkte)
- Synonyme
- CNX Protein, IP90 Protein, P90 Protein, 1110069N15Rik Protein, AI988026 Protein, Cnx Protein, D11Ertd153e Protein, canx Protein, clgn Protein, clnx Protein, cnx Protein, PP90 Protein, zgc:63524 Protein, wu:fe06b12 Protein, CANX Protein, calnexin Protein, CalNeXin Protein, calnexin L homeolog Protein, CANX Protein, Canx Protein, cnx-1 Protein, canx.L Protein, canx Protein, LOC100283947 Protein
- Hintergrund
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Abbreviation: CANX,Calnexin
Target Synonym: Calnexin,IP90,Major Histocompatibility Complex Class I Antigen-Binding Protein p88,p90,CANX
Background: Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
- Molekulargewicht
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Calculated MW: 30.69 kDa
Observed MW: 42 kDa
- UniProt
- P27824
- Pathways
- MAPK Signalweg, Thyroid Hormone Synthesis
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