IL28B Protein (AA 22-196) (His tag)

Produktnummer ABIN7505166

Produktdetails

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-196

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses IL28B Protein ist gelabelt mit His tag.

Sequenz: Val 22-Val 196

Produktmerkmale: A DNA sequence encoding the Human IL-28B/IFN-lambda-3 protein (Q8IZI9) (Val 22-Val 196) was expressed with N-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Andere Bezeichnung: IL-28B (IL28B Produkte)

Synonyme: Il28b Protein, IFL-1 Protein, IL-28B Protein, INF-alpha Protein, INF-lambda Protein, Il28 Protein, IL28B Protein, IL28C Protein, interferon, lambda 3 Protein, interferon lambda 3 Protein, Ifnl3 Protein, IFNL3 Protein

Hintergrund:

Abbreviation: IL-28B,IFN-lambda-3

Target Synonym: Interleukin-28B,IL-28B,Cytokine Zcyto22,Interferon Lambda-3,Interferon Lambda-4,IFN-Lambda-4,Interleukin-28C,IL-28C,IL28B,IFNL3,IFNL4,IL28C,ZCYTO22

Background: Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Molekulargewicht:

Calculated MW: 19.14 kDa

Observed MW: 25 kDa

UniProt: Q8IZI9