Kallikrein 2 Protein (KLK2) (AA 25-261) (His tag)

Produktnummer ABIN7505196

Produktdetails

Target: Kallikrein 2 (KLK2)

Protein-Typ: Recombinant

Proteineigenschaft: AA 25-261

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Kallikrein 2 Protein ist gelabelt mit His tag.

Sequenz: Ile 25-Pro 261

Produktmerkmale: A DNA sequence encoding the Human KLK2 protein (P20151) (Ile 25-Pro 261) was expressed with N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Kallikrein 2 (KLK2)

Andere Bezeichnung: KLK2 (KLK2 Produkte)

Synonyme: KLK2A2 Protein, hGK-1 Protein, hK2 Protein, KLK2 Protein, Ton Protein, rGK-2 Protein, Klk2 Protein, kallikrein related peptidase 2 Protein, kallikrein-related peptidase 2 Protein, kallikrein-2 Protein, kallikrein 1-related peptidase C2 Protein, KLK2 Protein, LOC748637 Protein, Klk1c2 Protein, LOC100716976 Protein

Hintergrund:

Abbreviation: KLK2

Target Synonym: Signal Transduction,Cell biology,Cancer

Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

Molekulargewicht:

Calculated MW: 25.96 kDa

Observed MW: 31 kDa

UniProt: P20151

Pathways: Komplementsystem