GABRB3 Protein (AA 26-245) (His tag)

Produktnummer ABIN7505216

Produktdetails

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-245

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GABRB3 Protein ist gelabelt mit His tag.

Sequenz: Ser 26-Tyr 245

Produktmerkmale: A DNA sequence encoding the Human GABRβ3(GABRB3) protein (P28472) (Ser 26-Tyr 245) was expressed with a C-His and N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Abstract: GABRB3 Produkte

Synonyme: GABRB3 Protein, eca5 Protein, LOC100230475 Protein, ECA5 Protein, A230092K12Rik Protein, AW049585 Protein, Cp1 Protein, Gabrb-3 Protein, beta3 Protein, gamma-aminobutyric acid type A receptor beta3 subunit Protein, gamma-aminobutyric acid (GABA) A receptor, beta 3 Protein, gamma-aminobutyric acid type A receptor beta 3 subunit Protein, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Protein, GABRB3 Protein, gabrb3 Protein, Gabrb3 Protein

Hintergrund:

Abbreviation: GABRβ3

Target Synonym: Gamma-aminobutyric acid receptor subunit beta-3,GABRB3,GABA(A) receptor subunit beta-3,GABRB3

Background: γ-aminobutyric acid type A receptor β3 subunit (GABRB3) is a candidate gene for autism spectrum conditions (ASC). Alteration in the gene results in increased tactile sensitivity, or hypersensitivity.Overexpression of GABRB3 might be implicated in the pathogenesis of heroin dependence. Aberration or mutation of this gene leads to neurodevelopmental disorders, such as Angelman syndrome, Prader-Willi syndrome and schizophrenia.[1][3] GABRB3 polymorphisms results in nonsyndromic cleft lip and/or palate (NSCL/P).

Molekulargewicht:

Calculated MW: 24.09 kDa

Observed MW: 32 kDa

UniProt: P28472

Pathways: Sensory Perception of Sound