RAD51 Protein (AA 2-339) (His tag)

Produktnummer ABIN7505246

Produktdetails

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-339

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RAD51 Protein ist gelabelt mit His tag.

Sequenz: Ala 2-Asp 339

Produktmerkmale: A DNA sequence encoding the Human Rad51 protein (Q06609) (Ala 2-Asp 339) was expressed with a N-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Andere Bezeichnung: Rad51 (RAD51 Produkte)

Synonyme: BRCC5 Protein, HRAD51 Protein, HsRad51 Protein, HsT16930 Protein, MRMV2 Protein, RAD51A Protein, RECA Protein, CRAD51 Protein, wu:fb38e12 Protein, zgc:77754 Protein, RGD1563603 Protein, ATRAD51 Protein, F22D1.20 Protein, F22D1_20 Protein, RAS associated with diabetes protein 51 Protein, AV304093 Protein, Rad51a Protein, Reca Protein, brcc5 Protein, rad51 Protein, rad51a Protein, reca Protein, xrad51 Protein, RAD51 recombinase Protein, RAS associated with diabetes protein 51 Protein, RAD51 recombinase L homeolog Protein, RAD51 Protein, rad51 Protein, Rad51 Protein, rad51.L Protein

Hintergrund:

Abbreviation: Rad51

Target Synonym: DNA repair protein RAD51 homolog 1,RAD51, HsRAD51,hRAD51

Background: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

Molekulargewicht:

Calculated MW: 37.07 kDa

Observed MW: 38 kDa

UniProt: Q06609

Pathways: DNA Reparatur