RAB5 Protein (AA 1-215) (His tag)
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- Target Alle RAB5 (RAB5A) Proteine anzeigen
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-215
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RAB5 Protein ist gelabelt mit His tag.
- Sequenz
- Met 1-Asn 215
- Produktmerkmale
- A DNA sequence encoding the Human RAB5A protein (P20339) (Met 1-Asn 215) was expressed with a N-His&C-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product RAB5A Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
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- Target
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
- Andere Bezeichnung
- RAB5A (RAB5A Produkte)
- Synonyme
- RAB5 Protein, 2410015H04Rik Protein, AI663973 Protein, AU021172 Protein, nnyRab5a Protein, DDBDRAFT_0168594 Protein, DDBDRAFT_0229401 Protein, DDB_0168594 Protein, DDB_0229401 Protein, rab5 Protein, RAB5A Protein, Rab5a Protein, rab5al Protein, zgc:56644 Protein, fj38g08 Protein, hm:zehn1144 Protein, rab5a Protein, wu:fj38g08 Protein, RAB5A, member RAS oncogene family Protein, rab5A protein Protein, Rab5a, GTPase Protein, predicted protein Protein, Rab GTPase Protein, RAB5A, member RAS oncogene family L homeolog Protein, RAB5A, member RAS oncogene family, b Protein, RAB5A, member RAS oncogene family, a Protein, RAB5A Protein, Rab5a Protein, rab5A Protein, rab5a Protein, rab5a.L Protein, rab5ab Protein, rab5aa Protein
- Hintergrund
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Abbreviation: RAB5A
Target Synonym: Ras-related protein Rab-5A,RAB5A
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
- Molekulargewicht
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Calculated MW: 23.54 kDa
Observed MW: 32 kDa
- UniProt
- P20339
- Pathways
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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