RBBP6 Protein (AA 1-313) (His tag)
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- Target Alle RBBP6 Produkte
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-313
- Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RBBP6 Protein ist gelabelt mit His tag.
- Sequenz
- Met 1-Lys 313
- Produktmerkmale
- A DNA sequence encoding the Human PACT protein (O75569) (Met 1-Lys 313) was expressed with a N-His&C-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
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- Target
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
- Andere Bezeichnung
- PACT (RBBP6 Produkte)
- Synonyme
- MY038 Protein, P2P-R Protein, PACT Protein, RBQ-1 Protein, SNAMA Protein, 4933422O15Rik Protein, AI316869 Protein, BB233631 Protein, C030034J04Rik Protein, C77662 Protein, rbbp6 Protein, MGC75882 Protein, RBBP6 Protein, im:7158869 Protein, rbbp6l Protein, RB binding protein 6, ubiquitin ligase Protein, retinoblastoma binding protein 6, ubiquitin ligase Protein, retinoblastoma binding protein 6 Protein, RBBP6 Protein, Rbbp6 Protein, rbbp6 Protein
- Hintergrund
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Abbreviation: PACT
Target Synonym: Interferon-inducible double-stranded RNA-dependent protein kinase activator A,PRKRA,PKR-associated protein X
Background: Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.
- Molekulargewicht
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Calculated MW: 34.32 kDa
Observed MW: 38 kDa
- UniProt
- O75569
- Pathways
- Regulatorische RNA Pathways
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