MFN2 Protein (AA 350-600) (His tag)

Produktnummer ABIN7505289

Produktdetails

Target: MFN2 (Mitofusin 2 (MFN2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 350-600

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MFN2 Protein ist gelabelt mit His tag.

Sequenz: Gln 350-Met 600

Produktmerkmale: A DNA sequence encoding the Human Mfn2 protein (O95140) (Gln 350-Met 600) was expressed with a N-His&C-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MFN2 (Mitofusin 2 (MFN2))

Andere Bezeichnung: Mfn2 (MFN2 Produkte)

Synonyme: CG3869 Protein, Dmel\\CG3869 Protein, MARF Protein, Marf-1 Protein, Mfn Protein, anon-WO0125274.3 Protein, dMFN Protein, dMfn Protein, dmfn Protein, marf Protein, mfn Protein, mfn2 Protein, MFN2 Protein, hsg Protein, cmt2a Protein, cprp1 Protein, cmt2a2 Protein, CMT2A Protein, CMT2A2 Protein, CPRP1 Protein, HSG Protein, D630023P19Rik Protein, Fzo Protein, mg:cb01g09 Protein, si:dkeyp-104h9.2 Protein, wu:fb79a11 Protein, mitofusin 2 Protein, Mitochondrial assembly regulatory factor Protein, mitofusin-2 Protein, mitofusin 2 L homeolog Protein, MFN2 Protein, Marf Protein, mfn2 Protein, LOC100186475 Protein, Mfn2 Protein, mfn2.L Protein

Hintergrund:

Abbreviation: Mfn2

Target Synonym: Mitofusin-2,MFN2,

Background: MFN-2 (Mitofusin 2, also Hypertension-related protein 1, Mitochondrial assembly regulatory factor, HSG protein, and Transmembrane GTPase MFN-2) is an 85?100 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. Through trans-interactions with MFN-1 and/or MFN-2, MFN-2 apparently mediates the fusion of individual mitochondria with either the ER or with adjacent mitochondria. Pertubations with this process result in both a general failure of mitochondria to fuse, and in cell-specific effects such as a reduction in oxidative phosphorylation, a decrease in the axonal transport of mitochondria, and a deficit in the expression of respiratory chain components. MFN-2 has two key domains.

Molekulargewicht:

Calculated MW: 27.5 kDa

Observed MW: 35 kDa

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development