MCM5 Protein (AA 1-200) (His tag)

Produktnummer ABIN7505292

Produktdetails

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-200

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MCM5 Protein ist gelabelt mit His tag.

Sequenz: Met 1-Asp 200

Produktmerkmale: A DNA sequence encoding the Human MCM5 protein (P33992) (Met 1-Asp 200) was expressed with a C-His,N-His.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Andere Bezeichnung: MCM5 (MCM5 Produkte)

Synonyme: 23.m06024 Protein, cdc46 Protein, xmcm5 Protein, CDC46 Protein, P1-CDC46 Protein, Afu5g02520 Protein, NCU01171.1 Protein, AA617332 Protein, AI324988 Protein, AL033333 Protein, Cdc46 Protein, Mcmd5 Protein, mCD46 Protein, mCDC46 Protein, mcm5 Protein, wu:fb34a06 Protein, CG4082 Protein, DmCDC46 Protein, DmCDC465 Protein, DmMCM5 Protein, DmMcm5 Protein, DmeMCM5 Protein, Dmel\\CG4082 Protein, MCM5 Protein, McM5 Protein, PCR4 Protein, DNA replication licensing factor MCM5 Protein, minichromosome maintenance complex component 5 S homeolog Protein, minichromosome maintenance complex component 5 Protein, DNA replication licensing factor Mcm5 Protein, DNA replication licensing factor mcm5 Protein, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) Protein, minichromosome maintenance complex component 5 L homeolog Protein, Minichromosome maintenance 5 Protein, DNA replication licensing factor mcm-5 Protein, BBOV_IV010040 Protein, mcm5.S Protein, MCM5 Protein, AFUA_5G02520 Protein, NCU01171 Protein, PVX_084615 Protein, LOC5576119 Protein, CpipJ_CPIJ008678 Protein, Bm1_24480 Protein, CMU_022890 Protein, Mcm5 Protein, mcm5 Protein, TP01_0722 Protein, mcm5.L Protein, mcm-5 Protein

Hintergrund:

Abbreviation: MCM5

Target Synonym: DNA replication licensing factor MCM5,MCM5, CDC46

Background: MCM5 (Mini Chromosome Maintainance protein-5) is involved in the control of DNA replication. MCM proteins have DNA dependent ATPase motifs in their central domain which is conserved from yeast to mammals. MCM proteins form a complex which exhibits ATPase and helicase activities. In G0 phase levels of MCM 2 and 5 are lower than that of MCM7 and 3 but increase as the cell enters G1/S phase of the cell cycle. It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy.

Molekulargewicht:

Calculated MW: 21.89 kDa

Observed MW: 35 kDa

UniProt: P33992-1

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA