FZD7 Protein (AA 31-250) (His tag)

Produktnummer ABIN7505306

Produktdetails

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Protein-Typ: Recombinant

Proteineigenschaft: AA 31-250

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FZD7 Protein ist gelabelt mit His tag.

Sequenz: Gly31-Arg250

Produktmerkmale: A DNA sequence encoding the Human Frizzled-7 protein (O75084) (Gly31-Arg250) was expressed with a C-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Andere Bezeichnung: Frizzled-7 (FZD7 Produkte)

Synonyme: FzE3 Protein, Fz-7 Protein, Xfz7 Protein, frizzled-7 Protein, frizzled7 Protein, frz-7 Protein, frz7 Protein, fz7 Protein, fzd7-a Protein, fzd7-b Protein, fze3 Protein, Fz7 Protein, cFz-7 Protein, fb38g02 Protein, fc44b09 Protein, fz13 Protein, fz7a Protein, fz7b Protein, wu:fb38g02 Protein, wu:fc44b09 Protein, zg13 Protein, frizzled class receptor 7 Protein, frizzled class receptor 7 L homeolog Protein, frizzled class receptor 7b Protein, FZD7 Protein, fzd7.L Protein, fzd7 Protein, Fzd7 Protein, fzd7b Protein

Hintergrund:

Abbreviation: Frizzled-7

Target Synonym: Frizzled-7,FZD7,

Background: Frizzled-7 is a member of the Frizzled family of unconventional G-protein-coupled glycoprotein receptors for the Wnt signaling pathway . The Wnt genes encode a large family of glycoproteins that are essential in development and tissue maintenance . Like other Frizzled family members, Frizzled-7 contains a divergent N-terminal signal peptide (amino acid (aa) 1 - 32), a highly conserved extracellular cysteine-rich domain (CRD, aa 44 - 169), a variable-length linker region (aa 170 ? 256), a seven-pass transmembrane region (aa 257 - 549), and a variable-length C-terminal cytoplasmic domain (aa 550 - 574) (1 - 3). The CRD, which comprises the binding site for Wnts and other ligands such as Syndecan 4 and fibronectin, spans about 130 amino acid residues and contains ten invariant cysteine residue

Molekulargewicht:

Calculated MW: 24.09 kDa

Observed MW: 32 kDa

UniProt: O75084

Pathways: WNT Signalweg, Stem Cell Maintenance