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S100A7A Protein (AA 1-108)

S100A7A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505349
  • Target Alle S100A7A Proteine anzeigen
    S100A7A (S100 Calcium Binding Protein A7A (S100A7A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-108
    Spezies
    • 5
    • 3
    • 1
    Maus
    Quelle
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    Met1-Tyr108
    Produktmerkmale
    Recombinant Mouse S100 calcium binding protein A15A is produced by our E.coli expression system and the target gene encoding Met1-Tyr108 is expressed.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product S100A7A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    S100A7A (S100 Calcium Binding Protein A7A (S100A7A))
    Andere Bezeichnung
    S100A15 (S100A7A Produkte)
    Synonyme
    NICE-2 Protein, S100A15 Protein, S100A7L1 Protein, S100A7f Protein, AY465109 Protein, Gm1020 Protein, S100a15 Protein, S100a15a Protein, S100a17l1 Protein, S100 calcium binding protein A7A Protein, Protein S100-A15A Protein, S100A7A Protein, S100a7a Protein, S100A15A Protein
    Hintergrund

    Abbreviation: S100A15;S100A7A

    Target Synonym: S100 calcium-binding protein A15A;Protein S100-A15A;Protein S100-A7A;S100 calcium-binding protein A7A;S100a15a

    Background: Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype. The association of the 11.2 kDa S100A7A / S100A15 with psoriasis suggests that it contributes to the pathogenesis of the disease and could provide a molecular target for therapy. 

    Molekulargewicht

    Calculated MW: 12.9 kDa

    Observed MW: 12 kDa

    UniProt
    Q6S5I3
    Pathways
    Activation of Innate immune Response, S100 Proteine
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