C3 Protein (AA 671-748) (TRX tag,His tag)
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- Target Alle C3 Proteine anzeigen
- C3 (Complement Component 3 (C3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 671-748
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses C3 Protein ist gelabelt mit TRX tag,His tag.
- Sequenz
- Ser 671-Arg 748
- Produktmerkmale
- A DNA sequence encoding the Mouse Component C3a protein (P01027) (Ser 671-Arg 748) was expressed with a N-Trx-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product C3 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
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- Target
- C3 (Complement Component 3 (C3))
- Abstract
- C3 Produkte
- Synonyme
- AHUS5 Protein, ARMD9 Protein, ASP Protein, C3a Protein, C3b Protein, CPAMD1 Protein, AI255234 Protein, HSE-MSF Protein, Plp Protein, C3 Protein, C3-1 Protein, sb:cb26 Protein, si:dkey-76b14.4 Protein, wu:fi34b03 Protein, wu:fj86e11 Protein, C3d Protein, asp Protein, cpamd1 Protein, c3 Protein, complement C3 Protein, complement component 3 Protein, complement component c3a, duplicate 1 Protein, complement component 3 L homeolog Protein, complement component C3 Protein, complement C3-like Protein, C3 Protein, c3a.1 Protein, c3.L Protein, LOC443475 Protein, c3 Protein, c3-1 Protein, LOC100060539 Protein
- Hintergrund
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Abbreviation: Component C3a
Target Synonym: Acylation stimulating protein,AHUS5,ARMD9,ASP,C3,Complement component C,Complement C3
Background: Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.
- Molekulargewicht
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Calculated MW: 28.47 kDa
Observed MW: 32 kDa
- UniProt
- P01027
- Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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