CBX5 Protein (AA 1-191) (His tag)

Produktnummer ABIN7505415

Produktdetails

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-191

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CBX5 Protein ist gelabelt mit His tag.

Sequenz: Met 1-Ser 191

Produktmerkmale: A DNA sequence encoding the Mouse HP1α protein (Q61686) (Met 1-Ser 191) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Andere Bezeichnung: HP1alpha (CBX5 Produkte)

Synonyme: HP1 Protein, HP1A Protein, id:ibd2026 Protein, wu:fc63e02 Protein, wu:fe47g12 Protein, wu:fi03h05 Protein, zgc:158601 Protein, CBX5 Protein, cbx5 Protein, MGC64354 Protein, 2610029O15Rik Protein, C75991 Protein, Hp1a Protein, Hp1alpha Protein, chromobox 5 Protein, chromobox homolog 5 (HP1 alpha homolog, Drosophila) Protein, chromobox 5 S homeolog Protein, CBX5 Protein, cbx5 Protein, Cbx5 Protein, cbx5.S Protein

Hintergrund:

Abbreviation: HP1α

Target Synonym: HP1 alpha,Antigen p25,CBX5,Chromobox 5,Epididymis luminal protein 25,HEL25,Heterochromatin protein 1,HP1A

Background: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Molekulargewicht:

Calculated MW: 20.9 kDa

Observed MW: 25 kDa

UniProt: Q61686