ABL1 Protein (AA 1-193) (His tag)
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- Target Alle ABL1 Proteine anzeigen
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-193
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses ABL1 Protein ist gelabelt mit His tag.
- Sequenz
- Met 1-Asn 193
- Produktmerkmale
- A DNA sequence encoding the Mouse ABL1/c-Abl protein (P00520) (Met 1-Asn 193) was expressed with N-His tag.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ABL1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
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- Target
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- Andere Bezeichnung
- ABL1 (ABL1 Produkte)
- Synonyme
- ABL Protein, JTK7 Protein, bcr/abl Protein, c-ABL Protein, p150 Protein, v-abl Protein, AI325092 Protein, Abl Protein, E430008G22Rik Protein, c-Abl Protein, ABL proto-oncogene 1, non-receptor tyrosine kinase Protein, c-abl oncogene 1, non-receptor tyrosine kinase Protein, Tyrosine-protein kinase abl-1 Protein, ABL1 Protein, Abl1 Protein, abl-1 Protein, abl1 Protein
- Hintergrund
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Abbreviation: ABL1,c-Abl
Target Synonym: Abelson tyrosine protein kinase 1,ABL 1,bcr/abl,JTK7,p150,Proto-oncogene c-Abl,v abl
Background: Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
- Molekulargewicht
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Calculated MW: 21.12 kDa
Observed MW: 25 kDa
- UniProt
- P00520
- Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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