TGFBR2 Protein (AA 371-592) (His tag)

Produktnummer ABIN7505427

Produktdetails

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 371-592

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TGFBR2 Protein ist gelabelt mit His tag.

Sequenz: Asp 371-Lys 592

Produktmerkmale: A DNA sequence encoding the Mouse TGFBR2 protein (Q62312) (Asp 371-Lys 592) was expressed with N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Andere Bezeichnung: TGFBR2 (TGFBR2 Produkte)

Synonyme: AAT3 Protein, FAA3 Protein, LDS1B Protein, LDS2B Protein, MFS2 Protein, RIIC Protein, TAAD2 Protein, TGFR-2 Protein, TGFbeta-RII Protein, 1110020H15Rik Protein, AU042018 Protein, DNIIR Protein, RIIDN Protein, TBR-II Protein, TbetaR-II Protein, TbetaRII Protein, TGFBR2 Protein, TBETA-RII Protein, TGFBRII Protein, TGF-beta 2 Protein, Tgfbr2T Protein, cb537 Protein, tgfbr2 Protein, wu:fj05c10 Protein, zgc:110498 Protein, transforming growth factor beta receptor 2 Protein, transforming growth factor, beta receptor II Protein, transforming growth factor, beta receptor 2 Protein, transforming growth factor beta receptor 2b Protein, TGFBR2 Protein, Tgfbr2 Protein, tgfbr2b Protein

Hintergrund:

Abbreviation: TGFBR2

Target Synonym: Transforming Growth Factor-Beta Receptor Type II,TGF-beta receptor type-2,TGFR-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II,TGF-beta receptor type II,TbetaR-II,Tgfbr2

Background: Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

Molekulargewicht:

Calculated MW: 24.31 kDa

Observed MW: 32 kDa

UniProt: Q62312