GSTP1 Protein (AA 2-210) (His tag)

Produktnummer ABIN7505432

Produktdetails

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-210

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GSTP1 Protein ist gelabelt mit His tag.

Sequenz: Pro 2-Gln 210

Produktmerkmale: A DNA sequence encoding the Mouse GSTp1 protein (P19157) (Pro 2-Gln 210) was expressed with N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Andere Bezeichnung: GSTp1 (GSTP1 Produkte)

Synonyme: DFN7 Protein, FAEES3 Protein, GST3 Protein, GSTP Protein, PI Protein, GST-P Protein, Gst3 Protein, Gstp Protein, Gstp2 Protein, gst-Pi Protein, GstpiB Protein, glutathione S-transferase P-like Protein, glutathione S-transferase pi 1 Protein, glutathione S-transferase pi 1 L homeolog Protein, glutathione S-transferase, pi 1 Protein, LOC100739163 Protein, GSTP1 Protein, Gstp1 Protein, LOC100861197 Protein, gstp1.L Protein

Hintergrund:

Abbreviation: GSTp1

Target Synonym: Glutathione S-transferase P,GSTP1,GST class-pi,GSTP1-1,FAEES3,GST3

Background: Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Molekulargewicht:

Calculated MW: 22.88 kDa

Observed MW: 28 kDa

UniProt: P19157

Pathways: Cellular Response to Molecule of Bacterial Origin