MMP12 Protein (AA 286-463) (His tag)

Produktnummer ABIN7505504

Produktdetails

Target: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Protein-Typ: Recombinant

Proteineigenschaft: AA 286-463

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MMP12 Protein ist gelabelt mit His tag.

Sequenz: Ala 286-Phe 463

Produktmerkmale: A DNA sequence encoding the Rat MMP-12 protein (Q63341) (Ala 286-Phe 463) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Andere Bezeichnung: MMP-12 (MMP12 Produkte)

Synonyme: MMP12 Protein, AV378681 Protein, Mmel Protein, Mme Protein, HME Protein, ME Protein, MME Protein, MMP-12 Protein, matrix metallopeptidase 12 Protein, MMP12 Protein, Mmp12 Protein

Hintergrund:

Abbreviation: MMP-12

Target Synonym: Macrophage metalloelastase,MME,Matrix metalloproteinase-12,MMP-12,Mmp12,Mme,Mmel

Background: Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Molekulargewicht:

Calculated MW: 19.47 kDa

Observed MW: 24 kDa

UniProt: Q63341