Angiopoietin 1 Protein (ANGPT1) (AA 304-450) (His tag)

Produktnummer ABIN7505509

Produktdetails

Target: Angiopoietin 1 (ANGPT1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 304-450

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Angiopoietin 1 Protein ist gelabelt mit His tag.

Sequenz: Asn304-Ala450

Produktmerkmale: A DNA sequence encoding the Rat ANG1 protein (O35460) (Asn304-Ala450) was expressed with a N-His .

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Angiopoietin 1 (ANGPT1)

Andere Bezeichnung: Angiopoietin-1 (ANGPT1 Produkte)

Synonyme: AGP1 Protein, AGPT Protein, ANG1 Protein, 1110046O21Rik Protein, Ang-1 Protein, Ang1 Protein, Agpt Protein, Agpt1 Protein, ang1 Protein, wu:fc76g06 Protein, ANG-1 Protein, angpt1 Protein, MGC80788 Protein, angiopoietin 1 Protein, angiopoietin 1 S homeolog Protein, ANGPT1 Protein, Angpt1 Protein, angpt1 Protein, angpt1.S Protein

Hintergrund:

Abbreviation: Angiopoietin-1,ANG1

Target Synonym: AGP1,AGPT,Ang1,ANG-1,angiopoietin 1,Angiopoietin-1,ANGPT1,ANGP1_RAT

Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

Molekulargewicht:

Calculated MW: 16.06 kDa

Observed MW: 18 kDa

UniProt: O35460

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process