PPARA Protein (AA 280-433) (His tag)

Produktnummer ABIN7505511

Produktdetails

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 280-433

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PPARA Protein ist gelabelt mit His tag.

Sequenz: Ser 280-Leu 433

Produktmerkmale: A DNA sequence encoding the Rat PPAR-α protein (P37230) (Ser 280-Leu 433) was expressed with a N-His tag.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Andere Bezeichnung: PPAR-alpha (PPARA Produkte)

Synonyme: NR1C1 Protein, PPAR Protein, PPARalpha Protein, hPPAR Protein, LOC100136415 Protein, PPARALPHA Protein, nr1c1 Protein, xPPARalpha Protein, xppara Protein, 4933429D07Rik Protein, AW742785 Protein, Nr1c1 Protein, PPAR-alpha Protein, Ppar Protein, peroxisome proliferator activated receptor alpha Protein, peroxisome proliferator-activated receptor alpha Protein, peroxisome proliferator activated receptor alpha L homeolog Protein, PPARA Protein, LOC100136415 Protein, ppara.L Protein, Ppara Protein, ppara Protein

Hintergrund:

Abbreviation: PPAR-α

Target Synonym: PPAR alpha,PPARA,PPARalpha,PPAR-alpha,PPARMGC2452

Background: Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha , NR1C1) is a member of the Nuclear Receptor superfamily. PPAR alpha exhibits the highest affinity with unsaturated fatty acids, and linolenic acids. PPAR alpha is expressed in brown fat, liver, kidney, heart, mucosa of the stomach and duodenum, retina, adrenal gland, skeletal muscle, pancreatic islets and smooth muscle cells. PPAR alpha plays important roles in lipid and glucose metabolism, and has been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three members have been identified and are called PPAR alpha, δ, and lambda. Retinoid X Receptor (RXR) is an obligate partner for PPAR.

Molekulargewicht:

Calculated MW: 16.83 kDa

Observed MW: 18 kDa

UniProt: P37230

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C